RICTOR Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14684-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14684-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14684-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14684-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
RICTOR
Background:
Rapamycin-insensitive companion of mTORis aproteinthat in humans is encoded by theRICTORgene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human RICTOR
Purification method:
Affinity purification
Target Synonym:
AVO3;AVO3 homolog;DKFZp686B11164;hAVO3;KIAA1999;Likely ortholog of mouse TORC2 specific protein AVO3 (S. cerevisiae);mAVO3;MGC39830;PIA;Pianissimo;Rapamycin insensitive companion of mTOR;Rapamycin-insensitive companion of mTOR;Rictor;RICTR;RICTR;RPTOR independent companion of MTOR complex 2;TORC2 specific protein AVO3
UNIProt ID:
Q6R327