RHOB Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12248-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12248-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12248-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12248-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
RHOB
Background:
Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
22kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000
Immunogen:
Synthetic peptide of human RHOB
Purification method:
Affinity purification
Target Synonym:
Aplysia RAS-related homolog 6;ARH6;ARHB;H6;MST081;MSTP081;oncogene RHO H6;ras homolog family member B;ras homolog gene family;member B;Rho cDNA clone 6;Rho related GTP binding protein RhoB Precursor;Rho-related GTP-binding protein RhoB;Rhob;RHOB;RHOH6
UNIProt ID:
P62745