REN Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14668-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14668-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14668-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14668-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
REN
Background:
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human REN
Purification method:
Affinity purification
Target Synonym:
Angiotensin forming enzyme;Angiotensin forming enzyme precursor;Angiotensinogenase;Angiotensinogenase precursor;FLJ10761;HNFJ2;REN;Ren1;RENI;Renin;Renin precursor renal
UNIProt ID:
P00797