DSCR1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16188-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16188-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16188-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16188-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
RCAN1
Background:
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
28kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human RCAN1
Purification method:
Affinity purification
Target Synonym:
Adapt 78;Adapt78;Calcipressin 1;Calcipressin-1;Calcium and oxidant inducible mRNA;CSP 1;CSP1;Down syndrome candidate region 1;Down syndrome critical region gene 1;Down syndrome critical region protein 1;DSC 1;DSC1;DSCR 1;DSCR1;MCIP 1;MCIP1;Modulatory calcineurin interacting protein 1;Myocyte enriched calcineurin interacting protein 1;Myocyte-enriched calcineurin-interacting protein 1;Near DSCR proline rich protein;RCAN1;RCAN1;RCN 1;RCN1;Regulator of calcineurin 1
UNIProt ID:
P53805