RBBP8 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14899-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14899-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14899-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14899-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
RBBP8
Background:
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Recombinant protein of human RBBP8
Purification method:
Affinity purification
Target Synonym:
COM1;COM1;CtBP interacting protein;CtBP-interacting protein;CtIP;DNA endonuclease RBBP8;JWDS;RB binding protein 8 endonuclease;RBBP-8;RBBP8;Retinoblastoma-binding protein 8;Retinoblastoma-interacting protein and myosin-like;Rim;SAE2;SCKL2;Sporulation in the absence of SPO11 protein 2 homolog
UNIProt ID:
Q99708