RASA2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13557-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13557-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13557-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13557-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
RASA2
Background:
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein; a compound suggested to function as a second messenger.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human RASA2
Purification method:
Affinity purification
Target Synonym:
GAP1m;GTPase activating protein of RAS;Ras GTPase activating protein 2;Ras GTPase-activating protein 2;RAS p21 protein activator 2;Rasa2;RASA2
UNIProt ID:
Q15283