PYGL Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11510-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11510-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11510-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11510-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PYGL
Background:
This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
97kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:30-1:150
Immunogen:
Recombinant protein of human PYGL
Purification method:
Affinity purification
Target Synonym:
Glycogen phosphorylase;Glycogen phosphorylase L;Glycogen phosphorylase liver;Glycogen phosphorylase liver form;GSD6;Hers disease;glycogen storage disease type VI;liver form;OTTHUMP00000233649;OTTHUMP00000233651;Phosphorylase glycogen liver;Pygl;PYGL
UNIProt ID:
P06737