NECTIN4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11438-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11438-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11438-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11438-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PVRL4
Background:
This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
55kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300
Immunogen:
Recombinant protein of human PVRL4
Purification method:
Affinity purification
Target Synonym:
DKFZp686K05193;EDSS1;Ig superfamily receptor LNIR;Nectin 4;Nectin-4;poliovirus receptor-related 4;Processed poliovirus receptor-related protein 4;PRR4;pvrl4;PVRL4
UNIProt ID:
Q96NY8