NECTIN1 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-15611-20uL | 20uL | £125.00 |
Quantity:
E-AB-15611-60uL | 60uL | £172.00 |
Quantity:
E-AB-15611-120uL | 120uL | £237.00 |
Quantity:
E-AB-15611-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
PVRL1
Background:
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
57kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Synthetic peptide of human PVRL1
Purification method:
Affinity purification
Target Synonym:
CD111;CD111 antigen;CLPED1;ectodermal dysplasia 4 (Margarita Island type);ED4;Herpes virus entry mediator C;Herpesvirus entry mediator C;Herpesvirus Ig like receptor;Herpesvirus Ig-like receptor;HIgR;HveC;MGC142031;Nectin 1;Nectin-1;OFC7;OROFACIAL CLEFT 7;OTTHUMP00000232093;OTTHUMP00000232094;OTTHUMP00000232095;Poliovirus receptor related protein 1;poliovirus receptor-like 1;Poliovirus receptor-related protein 1;PRR;PRR1;PVRL 1;PVRL1;PVRL1;PVRR;PVRR1;SK-12
UNIProt ID:
Q15223