PTPRM Polyclonal Antibody

PTPRM

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

1.1 mg/mL

Unconjugated

IHC 1:100-1:300

Synthetic peptide of human PTPRM

Affinity purification

hR PTPu;Protein tyrosine phosphatase mu;Protein tyrosine phosphatase receptor type M;Protein tyrosine phosphatase receptor type mu polypeptide;Protein-tyrosine phosphatase mu;PTPRL1;Ptprm;PTPRM;R PTP mu;R-PTP-mu;Receptor type tyrosine protein phosphatase mu;Receptor-type tyrosine-protein phosphatase mu;RPTPM;RPTPU

P28827