PTPRM Polyclonal Antibody
Code | Size | Price |
---|
E-AB-12853-20uL | 20uL | £125.00 |
Quantity:
E-AB-12853-60uL | 60uL | £172.00 |
Quantity:
E-AB-12853-120uL | 120uL | £237.00 |
Quantity:
E-AB-12853-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
PTPRM
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human PTPRM
Purification method:
Affinity purification
Target Synonym:
hR PTPu;Protein tyrosine phosphatase mu;Protein tyrosine phosphatase receptor type M;Protein tyrosine phosphatase receptor type mu polypeptide;Protein-tyrosine phosphatase mu;PTPRL1;Ptprm;PTPRM;R PTP mu;R-PTP-mu;Receptor type tyrosine protein phosphatase mu;Receptor-type tyrosine-protein phosphatase mu;RPTPM;RPTPU
UNIProt ID:
P28827