CD45 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-16319-20uL | 20uL | £125.00 |
Quantity:
E-AB-16319-60uL | 60uL | £172.00 |
Quantity:
E-AB-16319-120uL | 120uL | £237.00 |
Quantity:
E-AB-16319-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
PTPRC
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Synthetic peptide of human PTPRC
Purification method:
Affinity purification
Target Synonym:
B220;CD 45;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;Leukocyte common antigen;loc;Ly-5;LY5;Ly5;homolog of;Lyt-4;OTTHUMP00000033813;OTTHUMP00000033816;OTTHUMP00000033817;OTTHUMP00000038574;Protein tyrosine phosphatase receptor type c polypeptide;Protein tyrosine phosphatase;receptor type C;protein tyrosine phosphatase;receptor type;C;Protein tyrosine phosphatase;receptor type;c polypeptide;Ptprc;PTPRC;Receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen
UNIProt ID:
P08575
References
- https://onlinelibrary.wiley.com/doi/abs/10.1111/aji.13686
- https://www.spandidos-publications.com/10.3892/etm.2021.11095