SH-PTP1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-10587
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-10587-20uL20uL£125.00
Quantity:
E-AB-10587-60uL60uL£172.00
Quantity:
E-AB-10587-120uL120uL£237.00
Quantity:
E-AB-10587-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of A375 and A431 cell using SH-PTP1 Polyclonal Antibody at dilution of 1:500
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Immunohistochemistry of paraffin-embedded Human colon cancer using SH-PTP1 Polyclonal Antibody at dilution of 1:35
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Immunohistochemistry of paraffin-embedded Human liver cancer using SH-PTP1 Polyclonal Antibody at dilution of 1:35
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Western Blot analysis of A375 and A431 cell using SH-PTP1 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human colon cancer using SH-PTP1 Polyclonal Antibody at dilution of 1:35
Immunohistochemistry of paraffin-embedded Human liver cancer using SH-PTP1 Polyclonal Antibody at dilution of 1:35

Documents

Further Information

Abbreviation:
PTPN6
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
68kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human PTPN6
Purification method:
Affinity purification
Target Synonym:
70Z-SHP;EC 3.1.3.48;HCP;HCPH;Hematopoietic cell phosphatase;Hematopoietic cell protein tyrosine phosphatase;Hematopoietic cell protein-tyrosine phosphatase;HPTP1C;Protein tyrosine phosphatase 1C;Protein tyrosine phosphatase non receptor type 6;Protein tyrosine phosphatase SHP1;Protein-tyrosine phosphatase 1C;protein-tyrosine phosphatase SHP 1;Protein-tyrosine phosphatase SHP-1;PTN6;PTP 1C;PTP-1C;PTP1C;Ptpn6;SH PTP 1;SH PTP1;SH-PTP1;SHP 1;SHP 1L;SHP1;SHP1L;tyrosine protein phosphatase non receptor type 6;Tyrosine-protein phosphatase non-receptor type 6
UNIProt ID:
P29350