SH-PTP2 Polyclonal Antibody

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Elabscience
Product Code: E-AB-14341
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-14341-20uL20uL£125.00
Quantity:
E-AB-14341-60uL60uL£172.00
Quantity:
E-AB-14341-120uL120uL£237.00
Quantity:
E-AB-14341-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of NIH/3T3 and hela cell using SH-PTP2 Polyclonal Antibody at dilution of 1:400
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Western Blot analysis of NIH/3T3 and hela cell using SH-PTP2 Polyclonal Antibody at dilution of 1:400

Documents

Further Information

Abbreviation:
PTPN11
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
68kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Recombinant protein of human PTPN11
Purification method:
Affinity purification
Target Synonym:
BPTP3;CFC;JMML;METCDS;MGC14433;NS1;OTTHUMP00000166107;OTTHUMP00000166108;Protein tyrosine phosphatase 2;Protein tyrosine phosphatase 2C;Protein tyrosine phosphatase non receptor type 11;Protein-tyrosine phosphatase 1D;Protein-tyrosine phosphatase 2C;PTN11;PTP-1D;PTP-2C;PTP1D;PTP2C;PTPN11;SAP2;SH-PTP2;SH-PTP3;SH2 domain containing protein tyrosine phosphatase 2;SHP 2;SHP-2;Shp2;SHPTP2;SHPTP3;Syp;Tyrosine-protein phosphatase non-receptor type 11
UNIProt ID:
Q06124