PTN Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12851-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12851-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12851-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12851-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PTN
Background:
Pleiotrophin(PTN) also known asheparin-binding brain mitogen(HBBM) orheparin-binding growth factor 8(HBGF-8) orneurite growth-promoting factor 1(NEGF1) orheparin affinity regulatory peptide(HARP) orheparin binding growth associated molecule(HB-GAM) is aproteinthat in humans is encoded by thePTNgene.Pleiotrophin is an 18-kDagrowth factorthat has a high affinity forheparin. It is structurally related tomidkineandretinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
19kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Synthetic peptide of human PTN
Purification method:
Affinity purification
Target Synonym:
HARP;HB-GAM;HBBM;HBGAM;HBGF-8;HBGF8;HBNF;HBNF-1;HBNF1;heparin affin regulatory protein;Heparin binding growth associated molecule;Heparin binding growth factor 8;Heparin binding neurite outgrowth promoting factor 1;Heparin-binding brain mitogen;Heparin-binding growth factor 8;Heparin-binding growth-associated molecule;heparin-binding neurite outgrowth promoting factor;Heparin-binding neurite outgrowth-promoting factor 1;NEGF1;Neurite growth promoting factor 1;Neurite outgrowth-promoting factor;heparin-binding;OSF-1;OSF1;Osteoblast-specific factor 1;pleiotrophin (heparin binding growth factor 8;neurite growth-promoting factor 1);Pleiotrophin;PTN;PTN
UNIProt ID:
P21246