FAK Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12402-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12402-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12402-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12402-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PTK2
Background:
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
114kDa
Concentration:
1.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:2000-1:5000, IHC 1:100-1:300
Immunogen:
Synthetic peptide of human PTK2
Purification method:
Affinity purification
Target Synonym:
FADK 1;FADK;FAK related non kinase polypeptide;FAK1;FAK1;Focal adhesion kinase 1;Focal adhesion Kinase;Focal adhesion kinase isoform FAK Del33;Focal adhesion kinase related nonkinase;FRNK;p125FAK;pp125FAK;PPP1R71;Protein phosphatase 1 regulatory subunit 71;Protein tyrosine kinase 2;Protein-tyrosine kinase 2;Ptk2;PTK2 protein tyrosine kinase 2
UNIProt ID:
Q05397