PTCH1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10571-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10571-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10571-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10571-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PTCH1
Background:
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
161kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human PTCH1
Purification method:
Affinity purification
Target Synonym:
PTC;BCNS;HPE7;PTC1;PTCH;NBCCS;PTCH11
UNIProt ID:
Q13635
References
- https://www.sciencedirect.com/science/article/pii/S2352396419307820