PSMD9 Polyclonal Antibody

PSMD9

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

25kDa

0.4 mg/mL

Unconjugated

WB 1:500-1:2000, IHC 1:50-1:200

Recombinant protein of human PSMD9

Affinity purification

26S proteasome non ATPase regulatory subunit 9;26S proteasome non-ATPase regulatory subunit 9;26S proteasome regulatory subunit p27;Homolog of rat Bridge 1;MGC8644;p27;Proteasome (prosome macropain) 26S subunit non ATPase 9;Proteasome 26S non ATPase regulatory subunit 9;Proteasome 26S subunit non ATPase 9;PSMD 9;Psmd9;PSMD9;Rpn4

O00233