PSMD11 Polyclonal Antibody

PSMD11

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

0.8 mg/mL

Unconjugated

IHC 1:25-1:100

Synthetic peptide of human PSMD11

Affinity purification

26S proteasome non-ATPase regulatory subunit 11;26S proteasome regulatory subunit 9;26S proteasome regulatory subunit p44.5;26S proteasome regulatory subunit RPN6;26S proteasome regulatory subunit S9;MGC3844;p44.5;protease 26S;subunit;9;proteasome (prosome;macropain) 26S subunit;non-ATPase;11;proteasome 26S subunit;non-ATPase;11;PSD11;PSMD 11;PSMD11;Rpn6;S9

O00231