PSMC2 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-15216-20uL | 20uL | £125.00 |
Quantity:
E-AB-15216-60uL | 60uL | £172.00 |
Quantity:
E-AB-15216-120uL | 120uL | £237.00 |
Quantity:
E-AB-15216-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
PSMC2
Background:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
49kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human PSMC2
Purification method:
Affinity purification
Target Synonym:
26S protease complex;26S protease regulatory subunit 7;26S proteasome AAA-ATPase subunit RPT1;mammalian suppressor of sgv-1 of yeast;MSS1;Nbla10058;protease 26S subunit 7;proteasome 26S ATPase subunit 2;Proteasome 26S subunit ATPase 2;Proteasome 26S subunit ATPase 2;Protein MSS1;PRS7;PSMC2;putative protein product of Nbla10058;S7
UNIProt ID:
P35998