PSMC2 Polyclonal Antibody

PSMC2

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

49kDa

0.3 mg/mL

Unconjugated

WB 1:500-1:2000

Recombinant protein of human PSMC2

Affinity purification

26S protease complex;26S protease regulatory subunit 7;26S proteasome AAA-ATPase subunit RPT1;mammalian suppressor of sgv-1 of yeast;MSS1;Nbla10058;protease 26S subunit 7;proteasome 26S ATPase subunit 2;Proteasome 26S subunit ATPase 2;Proteasome 26S subunit ATPase 2;Protein MSS1;PRS7;PSMC2;putative protein product of Nbla10058;S7

P35998