PPP1R13L Polyclonal Antibody
Code | Size | Price |
---|
E-AB-15724-20uL | 20uL | £125.00 |
Quantity:
E-AB-15724-60uL | 60uL | £172.00 |
Quantity:
E-AB-15724-120uL | 120uL | £237.00 |
Quantity:
E-AB-15724-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
PPP1R13L
Background:
RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
89kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human PPP1R13L
Purification method:
Affinity purification
Target Synonym:
IASPP;inhibitor of apoptosis stimulating protein of p53;Inhibitor of ASPP protein;NFkB interacting protein 1;NKIP1;PPP1R13B-like protein;PPP1R13L;Protein iASPP;protein phosphatase 1 regulatory (inhibitor) subunit 13 like;RAI;RelA-associated inhibitor
UNIProt ID:
Q8WUF5