PPM1F Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16729-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16729-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16729-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16729-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PPM1F
Background:
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
50kDa
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human PPM1F
Purification method:
Affinity purification
Target Synonym:
Ca(2+)/calmodulin-dependent protein kinase phosphatase;CaM-kinase phosphatase;CAMKP;CaMKPase;FEM 2;hFEM-2;KIAA0015;Partner of PIX 2;POPX2;PP2C phosphatase;Ppm1f;PPM1F;Protein fem-2 homolog;Protein phosphatase 1F (PP2C domain containing);Protein phosphatase 1F;Protein phosphatase Mg2+/Mn2+ dependent 1F
UNIProt ID:
P49593