PNN Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16715-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16715-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16715-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16715-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PNN
Background:
Pinin is a desmosomal associated protein involved with the maintenance of cell to cell adhesion of the epithelium. Pinin is a widespread protein and has been shown to play an important role in cell adhesion through its interaction with nuclear complexes. Pinin is also involved in pre-mRNA splicing through its interactions with a C-terminal RS domain of Cyclophilin G, a Moca type nuclear cyclophilin. Pinin becomes nuclear during the early stages of embryonic development and remains so throughout the entire period. Defects or lack of Pinin can be lethal at perinatal stages and causes defects in the cardiac outflow tract, axial skeleton, palate and dorsal dermis.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human PNN
Purification method:
Affinity purification
Target Synonym:
140 kDa nuclear and cell adhesion-related phosphoprotein;Desmosome-associated protein;Domain-rich serine protein;DRS;DRS protein;DRSP;Melanoma metastasis clone A protein;MEMA;Nuclear protein SDK3;Pinin;PININ;PNN;SR like protein;SR-like protein
UNIProt ID:
Q9H307