PLEKHG6 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11416-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11416-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11416-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11416-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PLEKHG6
Background:
PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
89kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300
Immunogen:
Recombinant protein of human PLEKHG6
Purification method:
Affinity purification
Target Synonym:
FLJ10665;MGC126315;MGC126353;MGC126354;Myosin interacting guanine nucleotide exchange factor;PH domain containing family G member 6;Pleckstrin homology domain containing family G (with RhoGef domain) member 6;Pleckstrin homology domain-containing family G member 6;PLEKHG6
UNIProt ID:
Q3KR16