PLAT Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12879-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12879-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12879-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12879-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PLAT
Background:
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
63kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human PLAT
Purification method:
Affinity purification
Target Synonym:
Alteplase;DKFZp686I03148;Plasminogen activator tissue;Plasminogen activator tissue type;PLAT;Reteplase;t PA;T Plasminogen Activator;t-PA;T-plasminogen activator;Tissue plasminogen activator (t PA);Tissue type plasminogen activator;Tissue-type plasminogen activator chain B;tPA;TPA;TPA1
UNIProt ID:
P00750