PKM Polyclonal Antibody

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Elabscience
Product Code: E-AB-10004
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-10004-20uL20uL£125.00
Quantity:
E-AB-10004-60uL60uL£172.00
Quantity:
E-AB-10004-120uL120uL£237.00
Quantity:
E-AB-10004-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Hela cell using PKM Polyclonal Antibody at dilution of 1:500
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Immunohistochemistry of paraffin-embedded Human lung cancer using PKM Polyclonal Antibody at dilution of 1:50
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Western Blot analysis of Hela cell using PKM Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human lung cancer using PKM Polyclonal Antibody at dilution of 1:50

Documents

Further Information

Abbreviation:
PKM2
Background:
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
58kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human PKM2
Purification method:
Affinity purification
Target Synonym:
CTHBP;Cytosolic thyroid hormone binding protein;Cytosolic thyroid hormone-binding protein;KPYM;MGC3932;OIP 3;OIP-3;OIP3;OPA interacting protein 3;Opa-interacting protein 3;p58;PK muscle type;PK;muscle type;PK2;PK3;PKM;PKM2;pykm;Pyruvate kinase 2/3;Pyruvate kinase 3;Pyruvate kinase isozymes M1/M2;Pyruvate kinase muscle;Pyruvate kinase muscle isozyme;pyruvate kinase PKM;Pyruvate kinase;muscle 2;TCB;THBP1;Thyroid hormone binding protein 1;Thyroid hormone binding protein cytosolic;Thyroid hormone-binding protein 1;Tumor M2 PK;Tumor M2-PK
UNIProt ID:
P14618