PKD1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12437-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12437-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12437-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12437-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PKD1
Background:
This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1).
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human PKD1
Purification method:
Affinity purification
Target Synonym:
Autosomal dominant polycystic kidney disease 1 protein;Autosomal dominant polycystic kidney disease protein 1;nPKC-D1;nPKC-mu;OTTHUMP00000208669;OTTHUMP00000208670;PBP;Pc-1;PKD;Pkd1;PKD1;Polycystic Kidney Disease 1;polycystic kidney disease-associated protein;Polycystin 1 Precursor;Polycystin-1;Protein kinase C mu type;Protein kinase D;Serine/threonine-protein kinase D1;transient receptor potential cation channel;subfamily P;member 1;TRPP1
UNIProt ID:
P98161