PKC zeta Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-32609-20uL | 20uL | £125.00 |
Quantity:
| E-AB-32609-60uL | 60uL | £172.00 |
Quantity:
| E-AB-32609-120uL | 120uL | £237.00 |
Quantity:
| E-AB-32609-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Monkey
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PKC ζ
Background:
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
68kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Immunogen:
Synthesized peptide derived from human PKC ζ around the non-phosphorylation site of Thr560.
ObservedMW:
80kDa
Purification method:
Affinity purification
Target Synonym:
14-3-3-zetaisoform;AI098070;aPKCzeta;C80388;EC 2.7.11.13;KPCZ;nPKC zeta;nPKC-zeta;OTTHUMP00000001368;OTTHUMP00000044160;PKC 2;PKC ZETA;PKC2;Pkcz;PKCZETA;PKM-zeta;included;PRKCZ;Protein kinase C zeta;Protein kinase C zeta form;Protein kinase C zeta type;r14-3-3;R74924;zetaPKC
UNIProt ID:
Q05513
References
- https://journals.sagepub.com/doi/abs/10.1177/1010428317701442