PIM2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10916-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10916-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10916-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10916-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PIM2
Background:
This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human PIM2
Purification method:
Affinity purification
Target Synonym:
OTTHUMP00000025825;Pim 2 oncogene;Pim 2h;Pim-2h;PIM2;PIM2 Oncogene;PIM2;Pim2h;Proto Oncogene PIM2;Proto-oncogene Pim-2 (serine threonine kinase);Serine/threonine kinase PIM2;Serine/threonine-protein kinase Pim-2
UNIProt ID:
Q9P1W9