PIM1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14694-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14694-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14694-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14694-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PIM1
Background:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Recombinant protein of human PIM1
Purification method:
Affinity purification
Target Synonym:
Oncogene PIM 1;Oncogene PIM1;PIM 1;pim 1 kinase 44 kDa isoform;Pim 1 kinase;pim 1 oncogene (proviral integration site 1);Pim 1 oncogene;PIM;PIM1;pim1 kinase 44 kDa isoform;PIM1;Pim2;PIM3;Proto oncogene serine/threonine protein kinase Pim 1;Proto-oncogene serine/threonine-protein kinase Pim-1;Proviral integration site 1;Proviral integration site 2
UNIProt ID:
P11309