PIK3R3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13018-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13018-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13018-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13018-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PIK3R3
Background:
Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3? position. PI 3-kinase p55 (PIK3R3) is comprised of a catalytic subunit and a regulatory subunit. The human p55 protein is composed of a rare amino terminal region followed by a proline-rich motif and two Src homology 2 (SH2) domains. PI 3-kinase p55 mRNAs are expressed in most human fetal and adult tissues; predominant expression is observed in the adult testis. Splice variant(s) of PI 3-kinase p55 have been identified; one of which has a deletion of 36 amino acids at the amino terminus and another which has an insertion of 59 amino acids at position 256 between the SH2 domains. Research suggests that PI 3-kinase p55 interacts with the IGFIR (Insulin-like growth factor-I receptor) and IR (Insulin receptor) and may be involved in PI 3-kinase activation by these receptors.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100
Immunogen:
Synthetic peptide of human PIK3R3
Purification method:
Affinity purification
Target Synonym:
DKFZp686P05226;FLJ41892;OTTHUMP00000009783;OTTHUMP00000009786;p55;p55 gamma;P55G;p55PIK;Phosphatidylinositol 3 kinase regulatory subunit gamma;Phosphatidylinositol 3 kinase regulatory subunit polypeptide 3;Phosphatidylinositol 3 kinase;regulatory subunit;polypeptide 3 (p55;gamma);Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma;Phosphatidylinositol 3-kinase regulatory subunit gamma;Phosphoinositide 3 kinase regulatory subunit 3 (gamma);Phosphoinositide 3 kinase regulatory subunit 3;Phosphoinositide 3 kinase regulatory subunit polypeptide 3;Phosphoinositide 3 kinase;regulatory subunit 3 (p55;gamma);Phosphoinositide 3 kinase;regulatory subunit;polypeptide 3 (p55;gamma);PI3 kinase p85 subunit gamma;PI3-kinase regulatory subunit gamma;PI3-kinase subunit p55-gamma;PI3K regulatory subunit gamma;Pik3r3;PtdIns 3 kinase p85 gamma;PtdIns-3-kinase regulatory subunit gamma;PtdIns-3-kinase regulatory subunit p55-gamma
UNIProt ID:
Q92569