PIAS2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13005-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13005-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13005-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13005-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PIAS2
Background:
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human PIAS2
Purification method:
Affinity purification
Target Synonym:
Androgen receptor interacting protein 3;Androgen receptor-interacting protein 3;ARIP3;DAB2 interacting protein;DAB2-interacting protein;DIP;E3 SUMO protein ligase PIAS2;E3 SUMO-protein ligase PIAS2;MIZ;Miz1;Msx interacting zinc finger protein;Msx-interacting zinc finger protein;PIAS NY protein;PIAS-NY protein;PIAS2;PIAS2;PIASX;PIASX-ALPHA;PIASX-BETA;Protein inhibitor of activated STAT x;Protein inhibitor of activated STAT;2;Protein inhibitor of activated STAT2;SIZ2;Zinc finger;MIZ-type containing 4;ZMIZ4
UNIProt ID:
O75928