Phospho-MAP3K7 (Thr187) Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-21065-20uL | 20uL | £125.00 |
Quantity:
| E-AB-21065-60uL | 60uL | £172.00 |
Quantity:
| E-AB-21065-120uL | 120uL | £237.00 |
Quantity:
| E-AB-21065-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
Tak1 (phospho Thr187)
Background:
Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
67kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Immunogen:
Synthesized peptide derived from human Tak1 around the phosphorylation site of Thr187
ObservedMW:
60kDa
Purification method:
Affinity purification
Target Synonym:
M3K7;MAP3K 7;Map3k7;MEKK7;Mitogen activated protein kinase kinase kinase 7;Mitogen-activated protein kinase kinase kinase 7;TAK1;TGF beta activated kinase 1;TGF-beta-activated kinase 1;TGF1a;Transforming growth factor beta activated kinase 1;Transforming growth factor-beta-activated kinase 1
UNIProt ID:
O43318
References
- https://jpet.aspetjournals.org/content/364/3/399.abstract