Phospho-SMAD2/3 (Thr8) Polyclonal Antibody

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Elabscience
Product Code: E-AB-21040
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-21040-20uL20uL£125.00
Quantity:
E-AB-21040-60uL60uL£172.00
Quantity:
E-AB-21040-120uL120uL£237.00
Quantity:
E-AB-21040-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of VEC cells with Phospho-Smad2/3 (Thr8) Polyclonal Antibody
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Western Blot analysis of VEC cells with Phospho-Smad2/3 (Thr8) Polyclonal Antibody

Documents

Further Information

Abbreviation:
Smad2/3 (phospho Thr8)
Background:
SMAD is a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. They mediate the signal of the transforming growth factor (TGF)-beta, and thus regulate multiple cellular processes, such as cell proliferation, apoptosis, and differentiation.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
48kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:10000
Immunogen:
Synthesized peptide derived from human Smad2/3 around the phosphorylation site of Thr8
ObservedMW:
48kDa
Purification method:
Affinity purification
Target Synonym:
SMAD2;MADH2;MADR2;Mothers against decapentaplegic homolog 2;MAD homolog 2;Mothers against DPP homolog 2;JV18-1;Mad-related protein 2;hMAD-2;SMAD family member 2;SMAD 2;Smad2;hSMAD2;SMAD3;MADH3;Mothers against decapentaplegic
UNIProt ID:
Q15796,P84022

References

  • https://www.nature.com/articles/s41590-022-01166-6
  • https://www.mdpi.com/1333040
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006815/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631930/
  • https://www.sciencedirect.com/science/article/pii/S0024320521006895
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827317/
  • https://www.frontiersin.org/articles/10.3389/fphys.2020.00403/full?report=reader