Phospho-PKC delta (Thr507) Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-20968-20uL | 20uL | £125.00 |
Quantity:
| E-AB-20968-60uL | 60uL | £172.00 |
Quantity:
| E-AB-20968-120uL | 120uL | £237.00 |
Quantity:
| E-AB-20968-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PKC δ (phospho Thr507)
Background:
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
77kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Immunogen:
Synthesized peptide derived from human PKC δ around the phosphorylation site of Thr507
ObservedMW:
78kDa
Purification method:
Affinity purification
Target Synonym:
CVID9;D14Ertd420e;Kinase PKC delta;KPCD;KPCD;MAY 1;MAY1;MGC49908;nPKC delta;nPKC-delta;PCKd;PKC d;PKC delta;PKCD;PKCdelta;PRKC D;PRKC delta;Prkcd;Protein Kinase C delta;Protein kinase C delta type;Protein kinase C delta VIII;Protein Kinase Cdelta;Tyrosine protein kinase PRKCD
UNIProt ID:
Q05655
References
- https://www.frontiersin.org/articles/10.3389/fonc.2021.735183/full