Phospho-PAK1 (Thr212) Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-21179-20uL | 20uL | £125.00 |
Quantity:
| E-AB-21179-60uL | 60uL | £172.00 |
Quantity:
| E-AB-21179-120uL | 120uL | £237.00 |
Quantity:
| E-AB-21179-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PAKα (phospho Thr212)
Background:
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
61kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Immunogen:
Synthesized peptide derived from human PAKα around the phosphorylation site of Thr212
ObservedMW:
65kDa
Purification method:
Affinity purification
Target Synonym:
ADRB2;Alpha PAK;Alpha-PAK;MGC130000;MGC130001;p21 activated kinase 1;p21 protein (Cdc42/Rac) activated kinase 1;p21-activated kinase 1;p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related);p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog;yeast);p65 PAK;p65-PAK;P68-PAK;PAK alpha;PAK-1;Pak1;PAK1;Paka;PAKalpha;Protein kinase MUK2;Rac/p21-activated kinase;Serine/threonine-protein kinase PAK 1;STE20 homolog yeast
UNIProt ID:
Q13153
References
- https://onlinelibrary.wiley.com/doi/abs/10.1111/cns.13907