Phospho-IRS1 (Ser636) Polyclonal Antibody

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Elabscience
Product Code: E-AB-20908
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-20908-20uL20uL£125.00
Quantity:
E-AB-20908-60uL60uL£172.00
Quantity:
E-AB-20908-120uL120uL£237.00
Quantity:
E-AB-20908-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of SH-SY5Y cells using Phospho-IRS1 (Ser636) Polyclonal Antibody at dilution of 1:2000
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Western Blot analysis of SH-SY5Y cells using Phospho-IRS1 (Ser636) Polyclonal Antibody at dilution of 1:2000

Documents

Further Information

Abbreviation:
IRS-1 (phospho Ser636)
Background:
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
132kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Immunogen:
Synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser636
ObservedMW:
150kDa
Purification method:
Affinity purification
Target Synonym:
HIRS 1;HIRS1;Insulin receptor substrate 1;IRS 1;IRS-1;IRS1;IRS1;OTTHUMP00000164234
UNIProt ID:
P35568

References

  • https://www.mdpi.com/1422-0067/21/20/7744