Phospho-HDAC5 (Ser498) Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-20888-20uL | 20uL | £125.00 |
Quantity:
| E-AB-20888-60uL | 60uL | £172.00 |
Quantity:
| E-AB-20888-120uL | 120uL | £237.00 |
Quantity:
| E-AB-20888-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
HDAC5 (phospho Ser498)
Background:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
122kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Immunogen:
Synthesized peptide derived from human HDAC5 around the phosphorylation site of Ser498
ObservedMW:
122kDa
Purification method:
Affinity purification
Target Synonym:
Antigen NY CO 9;Antigen NY-CO-9;HD5;HDAC 5;HDAC5;HDAC5;Histone deacetylase 5;NY CO 9
UNIProt ID:
Q9UQL6