Phospho-Glucocorticoid Receptor (Ser211) Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-21144-20uL | 20uL | £125.00 |
Quantity:
| E-AB-21144-60uL | 60uL | £172.00 |
Quantity:
| E-AB-21144-120uL | 120uL | £237.00 |
Quantity:
| E-AB-21144-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
GR (phospho Ser211)
Background:
Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
86kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Immunogen:
Synthesized peptide derived from human GR around the phosphorylation site of Ser211
ObservedMW:
95kDa
Purification method:
Affinity purification
Target Synonym:
GCCR;GCR;GCR;GCRST;glucocorticoid nuclear receptor variant 1;Glucocorticoid receptor;GR;GRL;Grl1;nr3c1;Nuclear receptor subfamily 3 group C member 1;nuclear receptor subfamily 3;group C;member 1 (glucocorticoid receptor)
UNIProt ID:
P04150