Phospho-FLNA (Ser2152) Polyclonal Antibody

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Elabscience
Product Code: E-AB-21143
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-21143-20uL20uL£125.00
Quantity:
E-AB-21143-60uL60uL£172.00
Quantity:
E-AB-21143-120uL120uL£237.00
Quantity:
E-AB-21143-200uL200uL£344.00
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Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Monkey
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of HuvEc cells using Phospho-FLNA (Ser2152) Polyclonal Antibody at dilution of 1:2000
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Western Blot analysis of HuvEc cells using Phospho-FLNA (Ser2152) Polyclonal Antibody at dilution of 1:2000

Documents

Further Information

Abbreviation:
Filamin 1 (phospho Ser2152)
Background:
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
281kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Immunogen:
Synthesized peptide derived from human Filamin 1 around the phosphorylation site of Ser2152
ObservedMW:
280kDa
Purification method:
Affinity purification
Target Synonym:
ABP 280;ABP-280;Actin-binding protein 280;Alpha filamin;Alpha-filamin;APBX;CSBS;CVD1;Endothelial actin binding protein;Endothelial actin-binding protein;Filamin 1;Filamin A alpha;Filamin A;Filamin-1;Filamin-A;FLN;FLN-A;FLN1;FLNA;FLNA;FMD;MNS;NHBP;Non muscle filamin;Non-muscle filamin;OPD;OPD1;OPD2;XLVD;XMVD
UNIProt ID:
P21333