Phospho-EEF2K (Ser366) Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-21142-20uL | 20uL | £125.00 |
Quantity:
| E-AB-21142-60uL | 60uL | £172.00 |
Quantity:
| E-AB-21142-120uL | 120uL | £237.00 |
Quantity:
| E-AB-21142-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
eEF2K (phospho Ser366)
Background:
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
82kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Immunogen:
Synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366
ObservedMW:
105kDa
Purification method:
Affinity purification
Target Synonym:
C86191;Calcium/calmodulin dependent eukaryotic elongation factor 2;Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase;Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase;Calmodulin dependent protein kinase III;cb365;EC 2.7.11.20;eEF 2 kinase;eEF 2K;eEF-2 kinase;eEF-2K;Eef2k;EEF2K protein;EF2K;Elongation factor 2 kinase;Eukaryotic elongation factor 2 kinase;fa04b08;HSU93850;kinase eEF2K;MGC45041;SMEF2K;wu:fa04b08;zgc:100973
UNIProt ID:
O00418