Phospho-CREB1 (Ser133) Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-20849-20uL | 20uL | £125.00 |
Quantity:
| E-AB-20849-60uL | 60uL | £172.00 |
Quantity:
| E-AB-20849-120uL | 120uL | £237.00 |
Quantity:
| E-AB-20849-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CREB-1 (phospho Ser133)
Background:
This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
37kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300, ELISA 1:5000-1:20000
Immunogen:
Synthesized peptide derived from human CREB-1 around the phosphorylation site of Ser133
ObservedMW:
37kDa
Purification method:
Affinity purification
Target Synonym:
Active transcription factor CREB;cAMP response element binding protein 1;cAMP response element binding protein;cAMP responsive element binding protein 1;cAMP-responsive element-binding protein 1;CREB;CREB-1;CREB1;CREB1;Cyclic AMP-responsive element-binding protein 1;MGC9284;OTTHUMP00000163864;OTTHUMP00000163865;OTTHUMP00000206660;OTTHUMP00000206662;OTTHUMP00000206667;Transactivator protein
UNIProt ID:
P16220
References
- https://www.nature.com/articles/s41598-023-29287-4