PFN2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12624-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12624-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12624-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12624-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PFN2
Background:
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
15kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human PFN2
Purification method:
Affinity purification
Target Synonym:
D3S1319E;PFL;PFN 2;Pfn2;PROF2;Profilin II;Profilin-2;Profilin2;ProfilinII
UNIProt ID:
P35080