PERK Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-32546-20uL | 20uL | £125.00 |
Quantity:
| E-AB-32546-60uL | 60uL | £172.00 |
Quantity:
| E-AB-32546-120uL | 120uL | £237.00 |
Quantity:
| E-AB-32546-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PERK
Background:
Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1.
Buffer:
PBS with 0.02% sodium azide,0.5% protective protein and 50% glycerol pH 7.4.
Calculated MW:
125kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Immunogen:
Synthesized peptide derived from the N-terminal region of human PERK
ObservedMW:
125kDa
Purification method:
Affinity purification
Target Synonym:
DKFZp781H1925;E2AK3;EC 2.7.11.1;Eif2ak3;Eukaryotic translation initiation factor 2 alpha kinase 3;Eukaryotic translation initiation factor 2-alpha kinase 3;Heme regulated EIF2 alpha kinase;HRI;HsPEK;Pancreatic eIF2 alpha kinase;Pancreatic eIF2-alpha kinase;PEK;PRKR like endoplasmic reticulum kinase;PRKR-like endoplasmic reticulum kinase;WRS
UNIProt ID:
Q9NZJ5
References
- https://www.mdpi.com/1975256
- https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201986