PDX1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15824-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15824-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15824-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15824-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PDX1
Background:
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
31kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:15-1:50
Immunogen:
Synthetic peptide of human PDX1
Purification method:
Affinity purification
Target Synonym:
Glucose sensitive factor;Glucose-sensitive factor;GSF;IDX 1;IDX-1;IDX1;Insulin promoter factor 1;Insulin promoter factor 1 homeodomain transcription factor;Insulin upstream factor 1;IPF 1;IPF-1;IPF1;Islet/duodenum homeobox 1;Islet/duodenum homeobox-1;IUF 1;IUF-1;IUF1;MODY4;Pancreas/duodenum homeobox 1;Pancreas/duodenum homeobox protein 1;pancreatic and duodenal homeobox P;PDX 1;PDX-1;PDX1;PDX1;Somatostatin transactivating factor 1;Somatostatin-transactivating factor 1;STF 1;STF-1;STF1
UNIProt ID:
P52945