PDGFRB Polyclonal Antibody

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Elabscience
Product Code: E-AB-32531
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-32531-20uL20uL£125.00
Quantity:
E-AB-32531-60uL60uL£172.00
Quantity:
E-AB-32531-120uL120uL£237.00
Quantity:
E-AB-32531-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Hela, KB cells using PDGFRB Polyclonal Antibody at dilution of 1:1000.
2 / 2
Immunohistochemistry of paraffin-embedded Rat kidney using PDGFRB Polyclonal Antibody at dilution of 1:50
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Western Blot analysis of Hela, KB cells using PDGFRB Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Rat kidney using PDGFRB Polyclonal Antibody at dilution of 1:50

Documents

Further Information

Abbreviation:
PDGFR-β
Background:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
124kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Immunogen:
Synthesized peptide derived from human PDGFR-β around the non-phosphorylation site of Tyr751.
ObservedMW:
124kDa
Purification method:
Affinity purification
Target Synonym:
Beta platelet derived growth factor receptor;Beta-type platelet-derived growth factor receptor;CD 140B;CD140 antigen-like family member B;CD140b;CD140b antigen;IBGC4;IMF1;JTK12;OTTHUMP00000160528;PDGF R beta;PDGF-R-beta;PDGFR 1;PDGFR;PDGFR beta;PDGFR1;PDGFRB;PGFRB;Platelet derived growth factor receptor 1;Platelet derived growth factor receptor beta;Platelet derived growth factor receptor beta polypeptide
UNIProt ID:
P09619

References

  • https://www.liebertpub.com/doi/abs/10.1089/jir.2018.0113