PDE5A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16696-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16696-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16696-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16696-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
PDE5A
Background:
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Synthetic peptide of human PDE5A
Purification method:
Affinity purification
Target Synonym:
5''-cyclic phosphodiesterase;CGB PDE;CGB-PDE;CGBPDE;cGMP binding cGMP specific 3' 5' cyclic nucleotide phosphodiesterase;cGMP binding cGMP specific 35 cyclic nucleotide phosphodiesterase;cGMP binding cGMP specific phosphodiesterase;cGMP binding/cGMP specific phosphodiesterase;cGMP specific 3'5' cyclic phosphodiesterase;cGMP specific phosphodiesterase PDE5A2;cGMP specific phosphodiesterase type 5A;cGMP-binding cGMP-specific phosphodiesterase;cGMP-specific 3'';CN5A;CN5N;PDE 5;PDE 5A;PDE5;Pde5a;PDE5A;PDE5A1;Phosphodiesterase 5A;Phosphodiesterase 5A cGMP specific;Phosphodiesterase isozyme 5
UNIProt ID:
O76074
References
- https://www.sciencedirect.com/science/article/pii/S1043661822000536