NTRK1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12668-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12668-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12668-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12668-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NTRK1
Background:
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Synthetic peptide of human NTRK1
Purification method:
Affinity purification
Target Synonym:
gp140trk;High affinity nerve growth factor receptor;High affinity nerve growth factor receptor precursor;MTC;Neurotrophic tyrosine kinase receptor type 1;NTRK1;NTRK1;Oncogene TRK;p14-TrkA;p140 TrkA;p140-TrkA;Slow nerve growth;Trk A;TRK;Trk-A;TRK1;TRK1-transforming tyrosine kinase protein;Tropomyosin-related kinase A;Tyrosine kinase receptor A;Tyrosine kinase receptor
UNIProt ID:
P04629