NRG1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-16491
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-16491-20uL20uL£125.00
Quantity:
E-AB-16491-60uL60uL£172.00
Quantity:
E-AB-16491-120uL120uL£237.00
Quantity:
E-AB-16491-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Mouse brain tissue and A172 cell using NRG1 Polyclonal Antibody at dilution of 1:650
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Immunohistochemistry of paraffin-embedded Human colon cancer using NRG1 Polyclonal Antibody at dilution of 1:40
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Western Blot analysis of Mouse brain tissue and A172 cell using NRG1 Polyclonal Antibody at dilution of 1:650
Immunohistochemistry of paraffin-embedded Human colon cancer using NRG1 Polyclonal Antibody at dilution of 1:40

Documents

Further Information

Abbreviation:
NRG1
Background:
The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD).
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
70kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human NRG1
Purification method:
Affinity purification
Target Synonym:
Acetylcholine receptor-inducing activity;Acetylcholine receptor-inducing activity;CHICK;homolog of;ARIA;Breast cancer cell differentiation factor p45;GGF;GGF2;Glial growth factor;Heregulin;heregulin;alpha (45kD;ERBB2 p185-activator);HGL;HRG;HRG1;HRGA;MST131;NDF;Neu differentiation factor;Neuregulin 1;neuregulin 1 type IV beta 1a;neuregulin 1 type IV beta 3;Neuregulin-1;NRG 1;nrg1;NRG1-IT2;NRG1;OTTHUMP00000225398;OTTHUMP00000225419;OTTHUMP00000225420;OTTHUMP00000225421;OTTHUMP00000225422;OTTHUMP00000225477;OTTHUMP00000225545;OTTHUMP00000230603;OTTHUMP00000230605;pro-neuregulin-1;membrane-bound isoform;Pro-NRG1;ProNRG1;Sensory and motor neuron-derived factor;SMDF
UNIProt ID:
Q02297